Creed Humphrey was born on June 28, 1999, in Shawnee, Oklahoma. His father was a three-time All-American wrestler and Creed followed in his father’s footsteps. He said that his dad, “had me and my older brother in the wrestling room as soon as we could walk”. Both his mother and grandmother are survivors of breast cancer, and he said he learned toughness from them.
Creed attended Shawnee High School in Shawnee, Oklahoma where he played both center and defensive line as well as wrestled. He was a four-star prospect coming out of high school and rated the third-best center in the country. He received nineteen scholarship offers from schools including Alabama, Texas A&M, Texas, and others. He initially committed to Texas A&M in June 2016, but de-committed two months later and signed a letter of intent to go to Oklahoma.
He redshirted his first year in 2017. In 2018, he played all 14 games with 12 starts. The next two years he was the starting center and was named the Big 12 Conference’s offensive lineman of the year both seasons. After the 2020 season he declared for the 2021 draft, where he was selected by the Chiefs in the second round.