Melvin Ingram III was born on April 26, 1989, in Hamlet, North Carolina where he grew up and attended Richmond Senior High School in Rockingham, North Carolina. In high school he played everywhere – running back, fullback, linebacker and kicker. He was also the backup quarterback. His high school coach, Ed Emory, said, “He was a magician with that ball. He could throw the ball left and right-handed. He could kick with both feet.” That was just his sophomore year. By his junior year, he had settled in to spending most of his time at linebacker.
He was a four start recruit coming out of high school and was recruited by USC, North Carolina, and NC State. He chose South Carolina playing for Steve Spurrier. He played all four years there and was drafted by the Chargers as the 18th overall pick of the 2012 draft. In 2017, he was franchise tagged and signed a four-year contract. He finished the 2020 season on injured reserve with a knee injury, and in 2021 signed a one-year deal with the Steelers.
He was traded to the Chiefs for a sixth round pick on November 2, 2021.